![]() Differentially expressed RNAs (DERs) were identified, and functional enrichment analysis was performed. ![]() ![]() Expression profiles of long non-coding RNA (lncRNA), microRNA (miRNA), and messenger RNA (mRNA) were acquired from right atrial tissue samples of rats. This study aims to establish the regulatory networks based on whole-transcriptome RNA sequencing analyses and reveal the underlying mechanisms of cardiac fibrosis.Īn experimental model of myocardial fibrosis was induced using the chronic intermittent hypoxia (CIH) method. Cardiac fibrosis has gradually gained significance in the field of cardiovascular disease however, its specific pathogenesis remains unclear.
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